Showing posts with label Linked. Show all posts
Showing posts with label Linked. Show all posts

Friday, December 25, 2009

Another SSRI Linked to Birth Defects

Have for years, certain antidepressants in the press because of their link to birth defects among infants born to women who took the drug was born during the pregnancy. According to an article showing in the New England Journal of Medicine study published that "adopted children of mothers, Zoloft (sertraline generic born) or other SSRIs (Selective serotonin reuptake inhibitors) after the 20th week of pregnancy, six times more likely to have been persistent pulmonary hypertension (PPHN)than children of mothers who are not born to antidepressants during pregnancy. "

Babies born with PPHN have difficulty making the transition from breathing in the womb to normal breathing after birth. This difficulty often leads to respiratory failure that requires the use of a ventilator. Research has found that SSRIs can accumulate in the lungs of adults and serotonin cause the proliferation of certain muscle cells. This may explain the effect of the drug on the fetus. Between 10-20% of theChildren are not born with this disease survive.

The pharmaceutical company, Zoloft, Pfizer Incorporated, manufactures, promotes the drug for diseases in addition to depression, as many women may have been taking the drug, which has never been diagnosed with depression. Zoloft is also prescribed for social anxiety, panic disorder, treat post-traumatic stress disorder, premenstrual dysphoric disorder, and obsessive-compulsive disorder.

The fact that women may be dependent on Zoloft andother SSRIs still presents a different problem. Drugs associated with withdrawal symptoms to be very difficult for the patients and the recruitment of these drugs is something that is to be monitored closely by a doctor. However, continue taking Zoloft presents the additional problem of the child would be the trigger after he is born.

The research shows that almost one third of all infants born to women taking SSRIs born withdrawal symptoms such as trembling, high-pitched crying show, sleep disturbancesDisorders and gastrointestinal problems. An astonishing 13% of the 60 newborns exposed to SSRIs showed severe withdrawal symptoms.

If you are a pregnant woman, Zoloft or other SSRIs, you should contact your doctor immediately. If you suffer from a woman who has the Zoloft while you were pregnant, and your child PPHN, you can have a legitimate claim against the manufacturer of Zoloft.

Many people assume that because a drug is prescribed by a physician, it is safe;Unfortunately, this is not always the case. And, although the FDA monitors drugs before they are released to the public at large, dangerous side effects sometimes do not become apparent for years, according to the approved drugs.

Saturday, December 5, 2009

Diabetes Drug Linked to serious heart-related risks

Avandia generic rosiglitazone, was founded in 1999 by the FDA (Food and Drug Administration) for the treatment of type 2 diabetes. It is estimated that around six million people worldwide take the drug treatment of type 2 diabetes. An article published in the New England Journal of Medicine late in May 2007 found that among Avandia increases the risk of heart attacks in diabetes patients. In response to the article, the FDA issued a warning advising people taking public safetyAvandia to consult their doctor about the cardiovascular risks associated with taking the drug linked.

After analyzing dozens of studies, it was concluded that Avandia increases the risk of heart attack by 43% and heart-related deaths by 64%.

GlaxoSmithKline, the maker of Avandia, issued a press release to defend themselves and the drug. Glaxo is a challenge, the data in the New England Journal of Medicine presented study, stating that it is too early to be concluded thatAvandia increases the risk of cardiovascular problems in type-2 diabetes patients.

But in 2000, said Dr. John B. Buse, director of endocrinology at the University of North Carolina at Chapel Hill, wrote to the FDA warning that Avandia showed "a worrying development of cardiovascular deaths and severe adverse events "in patients taking the drug. In July 2001, the FDA Glaxo sent a letter in which the company's sales representatives had the drug affects the safety minimized, the FDAGlaxo asked to participate send a letter to doctors, Avandia, she warned of the serious risks associated with taking the drug prescription to be sent.

Obviously, both the FDA and the manufacturer of Avandia have known about the potential risks associated with cardiovascular drug for more than six years of association, but not sufficiently warn prescribers and consumers about the deadly effects of the drug. In 2000, Dr. Buse's letter to the FDA criticized Glaxo and the company gave the "pervasive and systemic" efforts toMinimizing overstate the drug benefits and drug benefits. The FDA sent a warning letter to doctors, but not taken decisive action has been, and continue to be prescribed the drug in the world.

Lawyers for Glaxo said they are always calls from Avandia users and predict future claims could reach into the tens of billions of dollars. Plaintiff lawyers certainly jack on the years of warnings about cardiovascular risks that were all but ignored by the developersAvandia.